Endoscopic ultrasound examination of the lesion described in Video clip 22. The radial echoendoscopic examination demonstrates a hypoechoic, somewhat heterogeneous mass lesion with well-defined borders measuring 36 mm × 38 mm. The exam is done in a back-and-forth motion over the lesion and demonstrates that the layer of origin of this lesion is the muscularis propria. Endoscopic ultrasound examination is most consistent with a GIST. This was confirmed on fine needle aspiration of this lesion.